I'm 24/7 and use my diaper 100%, and I've found MegaMax diapers work best for me. I could wear medium due to their sizing, but I prefer the large, so my diaper goes further up my back, wider crotch, and larger seat area. All of these reasons have helped me contain some rather large #2 loads, and sometimes for an extended period of time. And I've tried other diapers such as Rearz, ABU, Tykeables, and never had a #2 blowout.
I think if one is going to run a marathon, or do strenuous activities and wear for a long period, no diaper would be able to contain a huge mess in some situations. Also, it seems some ABDLs like to wear a messy diaper for long periods of time, that could case issues for sure. For me, 2-3 hours is max I can wear my messy diaper.