I did a little research on castration, the fastest anti-androgen procedure, and got to a couple of pages which showed an actual castration being performed which was icky pooh. On the other hand there's a web community of eunuchs. They write about a mental state they call The Eunuch Calm.
The operating principle is no androgens. I can achieve a close(r) state of calm by taking about 4 times the normal dose for girls-by-birth of progesterone/estrogen phyto equivalents. The best I have on that is called kwao krua, which comes from southeast asia. My breasts swell when I do that. And I have a lot less body hair, which wasn't much to begin with but it is so very noticeable.