Well, there is a few things.
1- Use some powder on your skin/diaper, but not enough to cause abrasions, just a light dusting on yoiur skin
2- Use as little more than the diaper and pants, skip the extra bits like underwear and covers if you can
3- Get used to it, over time your body will get used to the diaper
4- Can use something like a deodorant or i've been using the Hypo3 from munchkin for that and seems to work so far, keeps bacteria at bay.
I've been wearing 24/7 for a long time now for need and dont really feel any more sweaty than i did not is diapers, the diaper should absorb most of anything as it were too, so shouldnt be to "wet" maybe damp/clammy, but that is what it is.