I tend to get a little agitated if I haven't worn for more than 3 or 4 days, definitely. Though it varies somewhat, like if I'm traveling and don't take any diapers I might wish I had one but I'm usually distracted. I also wouldn't want to wear 24/7 either though. I get kind of tired of wearing just from being diapered in the evenings and at night for a few days. My preferred pattern is several days with diapers, then a couple days off and then back again.