I think everyone's different in this type of thing. e.g. my teeth are quite... mobile if you will.
When I had a retainer, even after a year of wearing it, taking it out for a night would cause a noticeable change in my teeth's position.
So, if I go a night or two without using a paci, putting it back in will hurt. If I'm using it nightly, it's fine after the first night.
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